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Titel:

Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis.

Dokumenttyp:
journal article
Autor(en):
EVOLVE Trial Investigators; Chertow, GM; Block, GA; Correa-Rotter, R; Drüeke, TB; Floege, J; Goodman, WG; Herzog, CA; Kubo, Y; London, GM; Mahaffey, KW; Mix, TC; Moe, SM; Trotman, ML; Wheeler, DC; Parfrey, PS; Chertow, G; Parfrey, P; Block, G; Correa-Rotter, R; Drüeke, T; Floege, J; Goodman, W; Herzog, C; London, G; Mahaffey, K; Moe, S; Wheeler, D; Hennekens, C; Baigent, C; Brown, W; O'Brien, P; Anderson, S; Hoel, J; Mahaffey, K; Szczech, L; Patel, U; Wampole, J; Pun, P; Felker, M; Inrig, J; Sha...     »
Abstract:
Disorders of mineral metabolism, including secondary hyperparathyroidism, are thought to contribute to extraskeletal (including vascular) calcification among patients with chronic kidney disease. It has been hypothesized that treatment with the calcimimetic agent cinacalcet might reduce the risk of death or nonfatal cardiovascular events in such patients.In this clinical trial, we randomly assigned 3883 patients with moderate-to-severe secondary hyperparathyroidism (median level of intact parath...     »
Zeitschriftentitel:
N Engl J Med
Jahr:
2012
Band / Volume:
367
Heft / Issue:
26
Seitenangaben Beitrag:
2482-94
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23121374
Print-ISSN:
0028-4793
TUM Einrichtung:
Abteilung für Nephrologie
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