In Arabidopsis, the leucine-rich receptor-like kinase STRUBBELIG (SUB) is involved in tissue morphogenesis of many organs. Structure-function analysis of SUB indicates that SUB accepts quite some sequence variation, reveal the biological importance for the SUB N-capping domain. The evidence indicates that biogenesis of a functional SUB receptor is subject to endoplasmic reticulum-mediated quality control. QUIRKY (QKY) belongs to STRUBBELIG-LIKE MUTANT (SLM) class of genes, encodes a novel multiple C2 domain containing transmembrane protein (MCTP). QKY binds to phospholipids in a Ca+2 dependent manner and has a similar expression domain as SUB. QKY and SUB are associated to plasmodesmata (PD) and growing cell plate during cytokinesis. Genetic and yeast-two-hybrid data indicate that SUB and QKY can interact directly. However, SUB and QKY do not appear to be involved in the non-selective movement of proteins through PD. The data imply that SUB signaling mediates tissue morphogenesis either by influencing selective transport of molecules through plasmodesmata or by regulating cytokinesis.
«
In Arabidopsis, the leucine-rich receptor-like kinase STRUBBELIG (SUB) is involved in tissue morphogenesis of many organs. Structure-function analysis of SUB indicates that SUB accepts quite some sequence variation, reveal the biological importance for the SUB N-capping domain. The evidence indicates that biogenesis of a functional SUB receptor is subject to endoplasmic reticulum-mediated quality control. QUIRKY (QKY) belongs to STRUBBELIG-LIKE MUTANT (SLM) class of genes, encodes a novel multip...
»