The examination included 578 school children aged 10-13 years from secondary schools in Munich, Germany. Diameters of retinal vessels and the arteriolar-to-venular ratio were measured using a static vessel-analyser. The objective was to reveal their relation to anthropometric data, components of the metabolic syndrome, low-grade inflammation (high sensitive c-reactive protein, hsCRP) and macrovascular elasticity (augmentation index, AIX). Obesity, as well as blood pressure, hsCRP and AIX, were associated with alterations of retinal vessel proportions. In contrast, serum lipides and fasting glucose had no independent influence. These data provide evidence that obesity could cause early retinal microvascular alterations in childhood.
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The examination included 578 school children aged 10-13 years from secondary schools in Munich, Germany. Diameters of retinal vessels and the arteriolar-to-venular ratio were measured using a static vessel-analyser. The objective was to reveal their relation to anthropometric data, components of the metabolic syndrome, low-grade inflammation (high sensitive c-reactive protein, hsCRP) and macrovascular elasticity (augmentation index, AIX). Obesity, as well as blood pressure, hsCRP and AIX, were a...
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