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Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Glanemann, M; Knobeloch, D; Ehnert, S; Culmes, M; Seeliger, C; Seehofer, D; Nüssler, AK
Title:
Hepatotropic growth factors protect hepatocytes during inflammation by upregulation of antioxidative systems.
Abstract:
To investigate effects of hepatotropic growth factors on radical production in rat hepatocytes during sepsis.Rat hepatocytes, isolated by collagenase perfusion, were incubated with a lipopolysaccharide (LPS)-containing cytokine mixture of interleukin-1?, tumor necrosis factor-? and interferon-? to simulate sepsis and either co-incubated or pre-incubated with hepatotropic growth factors, e.g. hepatocyte growth factor, epidermal growth factor and/or transforming growth factor-?. Cells were analyze...     »
Journal title abbreviation:
World J Gastroenterol
Year:
2011
Journal volume:
17
Journal issue:
17
Pages contribution:
2199-205
Language:
eng
Fulltext / DOI:
doi:10.3748/wjg.v17.i17.2199
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21633529
Print-ISSN:
1007-9327
TUM Institution:
Fachgebiet Gefäßchirurgie (Prof. Eckstein); Klinik und Poliklinik für Unfallchirurgie
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