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Title:

Myeloid RelA regulates pulmonary host defense networks.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Hess, C; Herr, C; Beisswenger, C; Zakharkina, T; Schmid, RM; Bals, R
Abstract:
The pulmonary innate immune system in the respiratory tract eliminates inhaled pathogens. Several cell types contribute to host defense within a complex network. The aim of this study was to evaluate the role of macrophages during pneumonia and in the regulation of the epithelial response to microorganisms. We performed lung infection models in mice lacking myeloid RelA/p65. To study the mechanistic relationships between individual cell types, we applied co-culture models composed of airway epit...     »
Journal title abbreviation:
Eur Respir J
Year:
2010
Journal volume:
35
Journal issue:
2
Pages contribution:
343-52
Language:
eng
Fulltext / DOI:
doi:10.1183/09031936.00196408
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19679599
Print-ISSN:
0903-1936
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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