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Title:

Future of local bone regeneration - Protein versus gene therapy.

Document type:
Journal Article
Author(s):
Fischer, J; Kolk, A; Wolfart, S; Pautke, C; Warnke, PH; Plank, C; Smeets, R
Abstract:
The most promising attempts to achieve bone regeneration artificially are based on the application of mediators such as bone morphogenetic proteins (BMPs) directly to the deficient tissue site. BMPs, as promoters of the regenerative process, have the ability to induce de novo bone formation in various tissues, and many animal models have demonstrated their high potential for ectopic and orthotopic bone formation. However, the biological activity of the soluble factors that promote bone formation...     »
Journal title abbreviation:
J Craniomaxillofac Surg
Year:
2011
Journal volume:
39
Journal issue:
1
Pages contribution:
54-64
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jcms.2010.03.016
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20434921
Print-ISSN:
1010-5182
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung; Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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