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Title:

Prognostic relevance of tumour cell-associated uPAR expression in invasive ductal breast carcinoma.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Kotzsch, M; Bernt, K; Friedrich, K; Luther, E; Albrecht, S; Gatzweiler, A; Magdolen, V; Baretton, G; Zietz, C; Luther, T
Abstract:
The urokinase-type plasminogen activator receptor (uPAR) is a key molecule for pericellular proteolysis in tumour cell invasion and metastasis. The aim was to evaluate the prognostic impact of uPAR in invasive breast cancer dependent on which cell types within the tumour express uPAR.uPAR expression was analysed by immunohistochemistry in 270 tumour tissue specimens of invasive ductal breast carcinomas using tissue microarrays. For evaluation of uPAR immunoexpression we used the epitope-mapped,...     »
Journal title abbreviation:
Histopathology
Year:
2010
Journal volume:
57
Journal issue:
3
Pages contribution:
461-71
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1365-2559.2010.03644.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20840675
Print-ISSN:
0309-0167
TUM Institution:
Frauenklinik und Poliklinik
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