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Title:

Co-detection of members of the urokinase plasminogen activator system in tumour tissue and serum correlates with a poor prognosis for soft-tissue sarcoma patients.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Taubert, H; Würl, P; Greither, T; Kappler, M; Bache, M; Lautenschläger, C; Fussel, S; Meye, A; Eckert, AW; Holzhausen, HJ; Magdolen, V; Kotzsch, M
Abstract:
BACKGROUND: The urokinase plasminogen activator (uPA) system is one of the best-investigated protease systems, both under physiological and pathological conditions, including various types of cancer. However, effects of co-expression of members of the uPA system in soft-tissue sarcoma (STS) patients at the protein level in both tumour tissue and serum have not been investigated yet. METHODS: We examined 82 STS patients for protein levels of uPA, PAI-1and uPAR in tumour tissue and serum by ELISA....     »
Journal title abbreviation:
Br J Cancer
Year:
2010
Journal volume:
102
Journal issue:
4
Pages contribution:
731-7
Language:
eng
Fulltext / DOI:
doi:10.1038/sj.bjc.6605520
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20051950
Print-ISSN:
0007-0920
TUM Institution:
Frauenklinik und Poliklinik
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