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Titel:

Free and Total Digoxin in Serum During Treatment of Acute Digoxin Poisoning With Fab Fragments: Case Study.

Dokumenttyp:
Journal Article
Autor(en):
Eyer, F; Steimer, W; Müller, C; Zilker, T
Abstract:
A woman ingested 10 mg of methyldigoxin in a suicide attempt and presented 19 hours after ingestion with clinical signs of glycoside intoxication. Her serum level of digoxin was 7.4 ng/mL, and antidotal therapy with Fab antibody fragments was started. The manufacturer's recommended dosing scheme was modified, with 80 mg Fab administered intravenously within 15 minutes followed by a continuous infusion at 30 mg/h. Total serum concentration of digoxin increased markedly within minutes after Fab th...     »
Zeitschriftentitel:
Am J Crit Care
Jahr:
2010
Band / Volume:
19
Heft / Issue:
4
Seitenangaben Beitrag:
391-387
Sprache:
eng
Volltext / DOI:
doi:10.4037/ajcc2009227
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19875723
Print-ISSN:
1062-3264
TUM Einrichtung:
2. Medizinische Klinik Toxikologische Abteilung (alt) (Prof. Zilker); Institut für Klinische Chemie und Pathobiochemie
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