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Titel:

Systematic evaluation of the miRNA-ome and its downstream effects on mRNA expression identifies gastric cancer progression.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Tchernitsa, O; Kasajima, A; Schäfer, R; Kuban, RJ; Ungethüm, U; Györffy, B; Neumann, U; Simon, E; Weichert, W; Ebert, MP; Röcken, C
Abstract:
We investigated the differential expression of Dicer and Drosha, as well as that of microRNA (miRNA), in adjacent normal and tumour samples of patients with gastric cancer. The expression of Dicer and Drosha was studied by immunohistochemistry in 332 gastric cancers and correlated with clinico-pathological patient characteristics. Differential expression of miRNAs was studied using the Invitrogen NCode((TM)) Multi-Species miRNA Microarray Probe Set containing 857 mammalian probes in a test set o...     »
Zeitschriftentitel:
J Pathol
Jahr:
2010
Band / Volume:
222
Heft / Issue:
3
Seitenangaben Beitrag:
310-9
Sprache:
eng
Volltext / DOI:
doi:10.1002/path.2759
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20726036
Print-ISSN:
0022-3417
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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