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Title:

Lupus nephritis reoccurs following transplantation in the lupus prone mouse.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Hamar, P; Wang, M; Godo, M; Kokeny, G; Rosivall, L; Ouyang, N; Heemann, U
Abstract:
The incidence and pathomechanism of recurrent lupus nephritis (RLN) after transplantation is not clearly understood. Burning out of the autoimmune process or local immunoregulatory mechanisms in the kidney may be responsible for the low incidence of recurrence. These mechanisms cannot be investigated in human subjects, due to post-transplant immunosuppression. To investigate the pathomechanisms of RLN, male and female kidneys were transplanted from FAS deficient lupus prone (LPR) or control (FAS...     »
Journal title abbreviation:
Lupus
Year:
2010
Journal volume:
19
Journal issue:
2
Pages contribution:
175-81
Language:
eng
Fulltext / DOI:
doi:10.1177/0961203309350753
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19946036
Print-ISSN:
0961-2033
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)
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