Parameter identification for modelling alveolar tissue on different scales

In this paper we focus on the material description of alveolar tissue. Two different approaches are presented; one models the tissue as a homogenized material (lung parenchyma) and the other one resolves the alveolar micro-structure. The material descriptions for both approaches are based on phenomenological strain-energy-functions. To identify the corresponding material parameters for each model noval experiments with vital tissue and an inverse analysis, using the Levenberg-Marquardt Algorithm, are utilized. The idea is to perform simulations of the experiments and vary the material parameters until the difference between the force-displacement curves obtained by the simulation and those in the experiments are within a given tolerance.     «

In this paper we focus on the material description of alveolar tissue. Two different approaches are presented; one models the tissue as a homogenized material (lung parenchyma) and the other one resolves the alveolar micro-structure. The material descriptions for both approaches are based on phenomenological strain-energy-functions. To identify the corresponding material parameters for each model noval experiments with vital tissue and an inverse analysis, using the Levenberg-Marquardt Algorith...     »