This prospective randomized study compares a porcine with a bovine bioprosthesis in the aortic position with regard to hemodynamic performance during exercise. Between August of 2000 and May of 2003, 139 patients underwent aortic valve replacement with the porcine Medtronic Mosaic (n = 67) or the bovine Carpentier-Edwards Perimount (n = 72) bioprosthesis. Transthoracic echocardiography was performed to assess hemodynamic and dimensional data preoperatively and 10 months postoperatively; the later follow-up included stress echocardiography. At rest and during exercise (25 and 50 W), there was a significant difference in mean pressure gradient between the bovine and the porcine valves with labeled sizes 21 and 23, with superiority of the Perimount prosthesis. Our data show a significant superiority of pressure gradients for the bovine bioprosthesis, especially with small valve sizes, when compared with the porcine device.      «

This prospective randomized study compares a porcine with a bovine bioprosthesis in the aortic position with regard to hemodynamic performance during exercise. Between August of 2000 and May of 2003, 139 patients underwent aortic valve replacement with the porcine Medtronic Mosaic (n = 67) or the bovine Carpentier-Edwards Perimount (n = 72) bioprosthesis. Transthoracic echocardiography was performed to assess hemodynamic and dimensional data preoperatively and 10 months postoperatively; the lat...     »