In this retrospective study, outcomes of 1053 women with hormone receptor positive non-metastasized breast cancer were analyzed, stratified by menopausal status and use of hormone therapy (HT) before diagnosis. 324 postmenopausal HT users had lower tumor stages, longer time to progression and higher overall survival (OS) than 296 non-users (p=0,28). 67 perimenopausal HT users, however, had a poorer prognosis than 52 perimenopausal non-users. Only in perimenopausal HT users a higher body mass index was associated with significantly worse OS (HR 1,31, 95% KI 1,11-1,54; p=0,001).
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In this retrospective study, outcomes of 1053 women with hormone receptor positive non-metastasized breast cancer were analyzed, stratified by menopausal status and use of hormone therapy (HT) before diagnosis. 324 postmenopausal HT users had lower tumor stages, longer time to progression and higher overall survival (OS) than 296 non-users (p=0,28). 67 perimenopausal HT users, however, had a poorer prognosis than 52 perimenopausal non-users. Only in perimenopausal HT users a higher body mass ind...
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