High-dose heparin (140 IU / kg) is associated with increased bleeding risk compared to bivalirudin in patients undergoing coronary intervention. In the ISAR-REACT 3A study, we compared 2505 patients with a reduced dose of heparin (100UI/Kg) with historical controls of bivalirudin and heparin High dose of ISAR-REACT 3 trial. The bleeding complications were significantly reduced by reducing the dose. Thus, the low-dose heparin consider not only the high-dose heparin with bivalirudin, but also comparable.
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High-dose heparin (140 IU / kg) is associated with increased bleeding risk compared to bivalirudin in patients undergoing coronary intervention. In the ISAR-REACT 3A study, we compared 2505 patients with a reduced dose of heparin (100UI/Kg) with historical controls of bivalirudin and heparin High dose of ISAR-REACT 3 trial. The bleeding complications were significantly reduced by reducing the dose. Thus, the low-dose heparin consider not only the high-dose heparin with bivalirudin, but also comp...
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