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Title:

Fermentation and purification process data boost the production of biopharmaceuticals.

Document type:
Nicht veröffentlichter Vortrag
Author(s):
Schömig, M.
Abstract:
Problem definition: Biopharmaceuticals are drugs derived from biological sources and produced large- scale using a two-stage biomanufacturing process. In the upstream process, cultivated cells produce the active pharmaceutical ingredient in a non-linear process with random yield. In the downstream process, chromatography resins are used to purify the target protein. Resins suffer from non-linear, random capacity decay. Both stages are often treated as two independent entities operated with fixed...     »
Event:
GPOM Workshop Winter 2023
Year:
2023
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