Recently the measurement of pulse wave velocity has gained increasing importance because this method provides the possibility of diagnosing an end organ damage of the arterial system. In this study patients with chronic kidney disease and renal transplant patients were subjected to a two-timed measurement of pulse wave velocity within an interval of one year. The change of the glomerular filtration rate (delta GFR) was equally observed. The hypothesis that there could be a correlation of the change of pulse wave velocity (delta PWV) with delta GFR was not confirmed. However, after subdividing of the cohort with chronic kidney disease in one group with diabetes mellitus and another without diabetes mellitus, significant differences between the subgroups regarding the parameters of pulse wave velocity were found. Furthermore the renal transplant cohort showed on the one hand a correlation of delta PWV with the blood pressure on the other hand a positive correlation of pulse wave velocity with albuminuria.
«