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Titel:

Role of T cells for cytokine production and outcome in a model of acute septic peritonitis.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Reim, D; Westenfelder, K; Kaiser-Moore, S; Schlautkötter, S; Holzmann, B; Weighardt, H
Abstract:
Although it is generally accepted that early defense mechanisms are controlled by cells of the innate immune system, T cells were found to be crucial for host resistance against acute septic peritonitis. However, the mechanisms by which T cells mediate protection are not fully understood. Here, we demonstrate mice deficient for recombinase-activating gene (RAG) 1, which lack mature B and T cells, showed enhanced susceptibility and impaired bacterial clearance in a model of acute septic peritonit...     »
Zeitschriftentitel:
Shock
Jahr:
2009
Band / Volume:
31
Heft / Issue:
3
Seitenangaben Beitrag:
245-50
Sprache:
eng
Volltext / DOI:
doi:10.1097/SHK.0b013e31817fd02c
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18650777
Print-ISSN:
1073-2322
TUM Einrichtung:
Chirurgische Klinik und Poliklinik; Urologische Klinik und Poliklinik
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