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Titel:

Intravesical alpha-radioimmunotherapy with 213Bi-anti-EGFR-mAb defeats human bladder carcinoma in xenografted nude mice.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Pfost, B; Seidl, C; Autenrieth, M; Saur, D; Bruchertseifer, F; Morgenstern, A; Schwaiger, M; Senekowitsch-Schmidtke, R
Abstract:
Transurethral resection of urothelial carcinoma often results in tumor recurrence due to disseminated tumor cells. Therefore, new therapeutic strategies are urgently needed. The aim of this study was to establish an orthotopic human bladder carcinoma mouse model using the epidermal growth factor receptor (EGFR)-overexpressing bladder carcinoma cell line EJ28 and to compare therapeutic efficacy of intravesically instilled alpha-particle-emitting (213)Bi-anti-EGFR-monoclonal antibody (mAb) with mi...     »
Zeitschriftentitel:
J Nucl Med
Jahr:
2009
Band / Volume:
50
Heft / Issue:
10
Seitenangaben Beitrag:
1700-8
Sprache:
eng
Volltext / DOI:
doi:10.2967/jnumed.109.065961
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19793735
Print-ISSN:
0161-5505
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Klinik und Poliklinik für Nuklearmedizin; Urologische Klinik und Poliklinik
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