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Title:

Pancreatic islet and stellate cells are the main sources of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 in pancreatic cancer.

Document type:
Journal Article; Article
Author(s):
Jiang, X; Abiatari, I; Kong, B; Erkan, M; De Oliveira, T; Giese, NA; Michalski, CW; Friess, H; Kleeff, J
Abstract:
AIMS: Endocrine gland-derived vascular endothelial growth factor (EG-VEGF)/prokineticins have been identified as tissue-specific angiogenic factors. This study investigates the expression and localization of EG-VEGF and its receptors in pancreatic tissues and pancreatic stellate cells (PSCs). METHODS: mRNA levels of EG-VEGF/prokineticin 1 (PK1), prokineticin 2 (PK2) and their receptors 1 (PKR1) and 2 (PKR2) were measured in pancreatic tissues, pancreatic cancer cell lines and PSCs by quantitativ...     »
Journal title abbreviation:
Pancreatology
Year:
2009
Journal volume:
9
Journal issue:
1-2
Pages contribution:
165-72
Language:
eng
Fulltext / DOI:
doi:10.1159/000178888
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19077468
Print-ISSN:
1424-3903
TUM Institution:
Chirurgische Klinik und Poliklinik
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