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Title:

Hypoxia Preconditioned Serum (HPS) Promotes Proliferation and Chondrogenic Phenotype of Chondrocytes In Vitro.

Document type:
Journal Article
Author(s):
Jiang, Jun; Altammar, Jannat; Cong, Xiaobin; Ramsauer, Lukas; Steinbacher, Vincent; Dornseifer, Ulf; Schilling, Arndt F; Machens, Hans-Günther; Moog, Philipp
Abstract:
Autologous chondrocyte implantation (ACI) for the treatment of articular cartilage defects remains challenging in terms of maintaining chondrogenic phenotype during in vitro chondrocyte expansion. Growth factor supplementation has been found supportive in improving ACI outcomes by promoting chondrocyte redifferentiation. Here, we analysed the chondrogenic growth factor concentrations in the human blood-derived secretome of Hypoxia Preconditioned Serum (HPS) and assessed the effect of HPS-10% and...     »
Journal title abbreviation:
Int J Mol Sci
Year:
2023
Journal volume:
24
Journal issue:
13
Fulltext / DOI:
doi:10.3390/ijms241310441
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37445617
Print-ISSN:
1422-0067
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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