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Title:

Comparative Evaluation of the Angiogenic Potential of Hypoxia Preconditioned Blood-Derived Secretomes and Platelet-Rich Plasma: An In Vitro Analysis.

Document type:
Journal Article
Author(s):
Moog, Philipp; Kirchhoff, Katharina; Bekeran, Sanjar; Bauer, Anna-Theresa; von Isenburg, Sarah; Dornseifer, Ulf; Machens, Hans-Günther; Schilling, Arndt F; Hadjipanayi, Ektoras
Abstract:
Blood-derived factor preparations are being clinically employed as tools for promoting tissue repair and regeneration. Here we set out to characterize the in vitro angiogenic potential of two types of frequently used autologous blood-derived secretomes: platelet-rich plasma (PRP) and hypoxia preconditioned plasma (HPP)/serum (HPS). The concentration of key pro-angiogenic (VEGF) and anti-angiogenic (TSP-1, PF-4) protein factors in these secretomes was analyzed via ELISA, while their ability to in...     »
Journal title abbreviation:
Biomedicines
Year:
2020
Journal volume:
8
Journal issue:
1
Fulltext / DOI:
doi:10.3390/biomedicines8010016
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31963131
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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