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Document type:
Journal Article
Author(s):
Kotliar, KE; Vilser, W; Schmidt-Trucksäss, A; Halle, M; Lanzl, IM
Title:
[Temporal oscillations of retinal vessel diameter in healthy volunteers of different age]
Abstract:
PURPOSE: We investigated whether temporal oscillations of the retinal vessel diameter, as measured with the dynamic vessel analyzer (DVA), undergo age-related changes. METHODS: Vessel diameters of retinal arterial and venous segments were examined with the DVA in 28 medically healthy volunteers divided into two age groups of 14 persons each: young subjects (21-32 years) and seniors (52-70 years). Continuous temporal records of vessel diameter were mathematically evaluated and divided into high-frequency (period <1.5 s) and low-frequency (period > or =1.5 s) oscillations. RESULTS: The phase difference between temporal arterial and venous vessel diameter records was higher in the young group [0.6 (0.1, 3.3)] s [median (1st quartile, 3rd quartile)] compared with the seniors [0.1 (-0.4, 0.3) s]. There was a difference in the periodicity in veins between the groups and, in seniors, between the arteries and the veins. CONCLUSIONS: High-frequency oscillations of vessel diameter correspond to the heartbeat. These were expressed more in seniors. Low-frequency oscillations were well expressed in young subjects. Our results show significant age-related alterations in retinal vessel regulation.
Journal title abbreviation:
Ophthalmologe
Year:
2009
Journal volume:
106
Journal issue:
7
Pages contribution:
609-18
Language:
de
Fulltext / DOI:
doi:10.1007/s00347-008-1878-9
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19381644
Print-ISSN:
0941-293X
TUM Institution:
Klinik und Poliklinik für Augenheilkunde; Poliklinik für Präventive und Rehabilitative Sportmedizin
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