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Titel:

IL13 variants are associated with total serum IgE and early sensitization to food allergens in children with atopic dermatitis.

Dokumenttyp:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Article
Autor(en):
Zitnik, SE; Rüschendorf, F; Müller, S; Sengler, C; Lee, YA; Griffioen, RW; Meglio, P; Wahn, U; Witt, H; Nickel, R
Abstract:
Increased total and specific serum immunoglobulin E (IgE) levels are common characteristics of atopic diseases and their basal production is proposed to be under strong genetic control. Interleukin 13 (IL13) variants have been consistently associated with total serum IgE levels in white populations with a strongest association in non-atopics. The aim of this study was to test the IL13 p.R130Q and c.1-1111C>T variants in children with atopic dermatitis (AD) for associations with total serum IgE a...     »
Zeitschriftentitel:
Pediatr Allergy Immunol
Jahr:
2009
Band / Volume:
20
Heft / Issue:
6
Seitenangaben Beitrag:
551-5
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1399-3038.2008.00815.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19220774
Print-ISSN:
0905-6157
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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