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Titel:

Functional analyses reveal the greater potency of preadipocytes compared with adipocytes as endothelial cell activator under normoxia, hypoxia, and TNFalpha exposure.

Dokumenttyp:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Mack, I; BelAiba, RS; Djordjevic, T; Gorlach, A; Hauner, H; Bader, BL
Abstract:
Obesity is associated with a state of chronic low-grade inflammation. Immune cells accumulate in white adipose tissue (WAT). The vascular endothelium plays an interactive role in these infiltration and inflammatory processes. Mature and hypertrophic adipocytes are considered as the major adipogenic cell type secreting proinflammatory cytokines in WAT. In contrast, the proinflammatory capacity of preadipocytes and their role in endothelial cell activation have been neglected so far. To gain new i...     »
Zeitschriftentitel:
Am J Physiol Endocrinol Metab
Jahr:
2009
Band / Volume:
297
Heft / Issue:
3
Seitenangaben Beitrag:
E735-48
Sprache:
eng
Volltext / DOI:
doi:10.1152/ajpendo.90851.2008
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19549791
Print-ISSN:
0193-1849
TUM Einrichtung:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin; Klinik für Kinderkardiologie und angeborene Herzfehler (Prof. Hess)
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