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Title:

Long-term risk of adverse outcomes and new malignancies in patients treated with oral sirolimus for prevention of restenosis.

Document type:
Journal Article; Randomized Controlled Trial
Author(s):
Kufner, S; Hausleiter, J; Ndrepepa, G; Schulz, S; Bruskina, O; Byrne, RA; Fusaro, M; Kastrati, A; Schömig, A; Mehilli, J
Abstract:
OBJECTIVES: We sought to investigate the long-term efficacy of oral sirolimus therapy and its impact on the incidence of de novo malignancies in the OSIRIS (Oral Sirolimus to Inhibit Recurrent In-Stent Stenosis) trial population. BACKGROUND: The OSIRIS trial showed a significant reduction of angiographic restenosis with an oral adjunctive sirolimus treatment for in-stent restenosis. The long-term efficacy of oral sirolimus therapy is unknown. METHODS: Three hundred patients with in-stent resteno...     »
Journal title abbreviation:
JACC Cardiovasc Interv
Year:
2009
Journal volume:
2
Journal issue:
11
Pages contribution:
1142-8
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jcin.2009.08.015
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19926058
Print-ISSN:
1936-8798
TUM Institution:
I. Medizinische Klinik und Poliklinik (Kardiologie); Institut für Radiologie
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