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Title:

Switch from aprotinin to ?-aminocaproic acid: impact on blood loss, transfusion, and clinical outcome in neonates undergoing cardiac surgery.

Document type:
Journal Article; Article
Author(s):
Martin, K; Gertler, R; Liermann, H; Mayr, NP; Macguill, M; Schreiber, C; Vogt, M; Tassani, P; Wiesner, G
Abstract:
With the withdrawal of aprotinin from worldwide marketing in November 2007, many institutions treating patients at high risk for hyperfibrinolysis had to update their therapeutic protocols. At our institution, the standard was switched from aprotinin to ?-aminocaproic acid (EACA) in all patients undergoing cardiac surgery with extracorporeal circulation including neonates. Although both antifibrinolytic medications have been used widely for many years, there are few data directly comparing their...     »
Journal title abbreviation:
Br J Anaesth
Year:
2011
Journal volume:
107
Journal issue:
6
Pages contribution:
934-9
Language:
eng
Fulltext / DOI:
doi:10.1093/bja/aer267
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21857014
Print-ISSN:
0007-0912
TUM Institution:
Fachgebiet Kardioanästhesie (Prof. Tassani-Prell); Klinik für Herz- und Gefäßchirurgie (Prof. Lange)
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