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Title:

Evaluation of polycaprolactone scaffold degradation for 6 months in vitro and in vivo.

Document type:
Journal Article
Author(s):
Lam, CX; Hutmacher, DW; Schantz, JT; Woodruff, MA; Teoh, SH
Abstract:
The use of polycaprolactone (PCL) as a biomaterial, especially in the fields of drug delivery and tissue engineering, has enjoyed significant growth. Understanding how such a device or scaffold eventually degrades in vivo is paramount as the defect site regenerates and remodels. Degradation studies of three-dimensional PCL and PCL-based composite scaffolds were conducted in vitro (in phosphate buffered saline) and in vivo (rabbit model). Results up to 6 months are reported. All samples recorded...     »
Journal title abbreviation:
J Biomed Mater Res A
Year:
2009
Journal volume:
90
Journal issue:
3
Pages contribution:
906-19
Language:
eng
Fulltext / DOI:
doi:10.1002/jbm.a.32052
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18646204
Print-ISSN:
1549-3296
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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