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Titel:

Evaluation of polycaprolactone scaffold degradation for 6 months in vitro and in vivo.

Dokumenttyp:
Journal Article
Autor(en):
Lam, CX; Hutmacher, DW; Schantz, JT; Woodruff, MA; Teoh, SH
Abstract:
The use of polycaprolactone (PCL) as a biomaterial, especially in the fields of drug delivery and tissue engineering, has enjoyed significant growth. Understanding how such a device or scaffold eventually degrades in vivo is paramount as the defect site regenerates and remodels. Degradation studies of three-dimensional PCL and PCL-based composite scaffolds were conducted in vitro (in phosphate buffered saline) and in vivo (rabbit model). Results up to 6 months are reported. All samples recorded...     »
Zeitschriftentitel:
J Biomed Mater Res A
Jahr:
2009
Band / Volume:
90
Heft / Issue:
3
Seitenangaben Beitrag:
906-19
Sprache:
eng
Volltext / DOI:
doi:10.1002/jbm.a.32052
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18646204
Print-ISSN:
1549-3296
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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