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Title:

Involvement of Group II mGluRs in mossy fiber LTD.

Document type:
In Vitro; Journal Article
Author(s):
Wostrack, M; Dietrich, D
Abstract:
Mossy fiber long-term depression (LTD) has been shown to be triggered by either pharmacological or synaptic activation of Group II metabotropic glutamate receptors (mGluRs) whereas other studies indicate that synaptic activation of mGluRs is very limited. Therefore, we reexamined the role of Group II mGluRs for the induction of mossy fiber LTD. The complete depression of field potentials (fEPSPs) by 1 microM (2S,2'R,3'R)-2-(2',3'-Dicarboxycyclopropyl)glycine (DCG-IV) only partially reversed upon...     »
Journal title abbreviation:
Synapse
Year:
2009
Journal volume:
63
Journal issue:
12
Pages contribution:
1060-8
Language:
eng
Fulltext / DOI:
doi:10.1002/syn.20692
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19637276
Print-ISSN:
0887-4476
TUM Institution:
Neurochirurgische Klinik und Poliklinik
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