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Title:

Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel

Document type:
Article
Author(s):
Sibbing, D; Morath, T; Stegherr, J; Braun, S; Vogt, W; Hadamitzky, M; Schömig, A; Kastrati, A; von Beckerath, N
Abstract:
Patients receiving dual antiplatelet treatment with aspirin and clopidogrel are commonly treated with proton pump inhibitors (PPIs). Attenuating effects on platelet response to clopidogrel have been reported solely for the PPI omeprazole. PPIs differ in their metabolisation properties as well as their potential for drug-drug interactions. The aim of this study was to investigate the impact of different PPIs (pantoprazole, omeprazole, esomeprazole) on platelet response to clopidogrel in patients...     »
Journal title abbreviation:
J Thromb Haemost
Year:
2009
Journal volume:
101
Journal issue:
4
Pages contribution:
714-719
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19350116
Print-ISSN:
1538-7933
TUM Institution:
I. Medizinische Klinik und Poliklinik (Kardiologie); Institut für Laboratoriumsmedizin (keine SAP-Zuordnung!)
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