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Title:

Biosensor analyses of serum autoantibodies: application to antiphospholipid syndrome and systemic lupus erythematosus.

Document type:
Journal Article
Author(s):
Thaler, M; Buhl, A; Welter, H; Schreiegg, A; Kehrel, M; Alber, B; Metzger, J; Luppa, PB
Abstract:
Autoimmune disorders are rare human diseases characterized by the presence of circulating autoantibodies that bind the body's own structural compounds as target antigens. The detection of autoantibodies is important for the diagnostic process. Immunofluorescence and immunoassay methods do not allow a reliable characterization of binding characteristics. Therefore, novel analytical techniques should be considered. This review describes the application of surface plasmon resonance biosensor system...     »
Journal title abbreviation:
Anal Bioanal Chem
Year:
2009
Journal volume:
393
Journal issue:
5
Pages contribution:
1417-29
Language:
eng
Fulltext / DOI:
doi:10.1007/s00216-008-2340-1
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18759105
Print-ISSN:
1618-2642
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie
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