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Titel:

Simultaneous expression of Cathepsins B and K in pulmonary adenocarcinomas and squamous cell carcinomas predicts poor recurrence-free and overall survival.

Dokumenttyp:
Journal Article; Article
Autor(en):
Cordes, C; Bartling, B; Simm, A; Afar, D; Lautenschläger, C; Hansen, G; Silber, RE; Burdach, S; Hofmann, HS
Abstract:
PURPOSE: Patient survival after resection of non-small cell lung cancer (NSCLC) strongly correlated with the occurrence of distant metastasis. Cathepsins are members of the lysosomal cysteine proteases family and can support the metastatic process by degrading the extracellular matrix. The purpose of this study was to identify members of the Cathepsin family that correlate with recurrence-free and overall survival of NSCLC patients. PATIENTS AND METHODS: The expression of 13 Cathepsins was exami...     »
Zeitschriftentitel:
Lung Cancer
Jahr:
2009
Band / Volume:
64
Heft / Issue:
1
Seitenangaben Beitrag:
79-85
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.lungcan.2008.07.005
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18760860
Print-ISSN:
0169-5002
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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