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Titel:

HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Winkler, C; Illig, T; Koczwara, K; Bonifacio, E; Ziegler, AG
Abstract:
CONTEXT: The fetal insulin hypothesis proposes that common genetic variants that reduce insulin secretion also reduce birth weight, and an association of low birth weight and the type 2 diabetes risk alleles at the HHEX-IDE and CDKAL1 loci were recently reported. OBJECTIVE: Here, we examined the relationship between type 2 diabetes risk alleles and birth weight in a diabetic environment presented in children of mothers with type 1 diabetes. RESEARCH DESIGN AND METHODS: Birth weight and genotypin...     »
Zeitschriftentitel:
J Clin Endocrinol Metab
Jahr:
2009
Band / Volume:
94
Heft / Issue:
10
Seitenangaben Beitrag:
4113-5
Sprache:
eng
Volltext / DOI:
doi:10.1210/jc.2009-0970
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19622614
Print-ISSN:
0021-972X
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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