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Title:

Use of tumour-responsive T cells as cancer treatment.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
Author(s):
Disis, ML; Bernhard, H; Jaffee, EM
Abstract:
The stimulation of a tumour-specific T-cell response has several theoretical advantages over other forms of cancer treatment. First, T cells can home in to antigen-expressing tumour deposits no matter where they are located in the body-even in deep tissue beds. Additionally, T cells can continue to proliferate in response to immunogenic proteins expressed in cancer until all the tumour cells are eradicated. Finally, immunological memory can be generated, allowing for eradication of antigen-beari...     »
Journal title abbreviation:
Lancet
Year:
2009
Journal volume:
373
Journal issue:
9664
Pages contribution:
673-83
Language:
eng
Fulltext / DOI:
doi:10.1016/S0140-6736(09)60404-9
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19231634
Print-ISSN:
0140-6736
TUM Institution:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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