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Titel:

Use of tumour-responsive T cells as cancer treatment.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
Autor(en):
Disis, ML; Bernhard, H; Jaffee, EM
Abstract:
The stimulation of a tumour-specific T-cell response has several theoretical advantages over other forms of cancer treatment. First, T cells can home in to antigen-expressing tumour deposits no matter where they are located in the body-even in deep tissue beds. Additionally, T cells can continue to proliferate in response to immunogenic proteins expressed in cancer until all the tumour cells are eradicated. Finally, immunological memory can be generated, allowing for eradication of antigen-beari...     »
Zeitschriftentitel:
Lancet
Jahr:
2009
Band / Volume:
373
Heft / Issue:
9664
Seitenangaben Beitrag:
673-83
Sprache:
eng
Volltext / DOI:
doi:10.1016/S0140-6736(09)60404-9
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19231634
Print-ISSN:
0140-6736
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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