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Titel:

Host defense peptides as effector molecules of the innate immune response: a sledgehammer for drug resistance?

Dokumenttyp:
Journal Article
Autor(en):
Steinstraesser, L; Kraneburg, UM; Hirsch, T; Kesting, M; Steinau, HU; Jacobsen, F; Al-Benna, S
Abstract:
Host defense peptides can modulate the innate immune response and boost infection-resolving immunity, while dampening potentially harmful pro-inflammatory (septic) responses. Both antimicrobial and/or immunomodulatory activities are an integral part of the process of innate immunity, which itself has many of the hallmarks of successful anti-infective therapies, namely rapid action and broad-spectrum antimicrobial activities. This gives these peptides the potential to become an entirely new thera...     »
Zeitschriftentitel:
Int J Mol Sci
Jahr:
2009
Band / Volume:
10
Heft / Issue:
9
Seitenangaben Beitrag:
3951-70
Sprache:
eng
Volltext / DOI:
doi:10.3390/ijms10093951
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19865528
Print-ISSN:
1422-0067
TUM Einrichtung:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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