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Title:

Host defense peptides as effector molecules of the innate immune response: a sledgehammer for drug resistance?

Document type:
Journal Article
Author(s):
Steinstraesser, L; Kraneburg, UM; Hirsch, T; Kesting, M; Steinau, HU; Jacobsen, F; Al-Benna, S
Abstract:
Host defense peptides can modulate the innate immune response and boost infection-resolving immunity, while dampening potentially harmful pro-inflammatory (septic) responses. Both antimicrobial and/or immunomodulatory activities are an integral part of the process of innate immunity, which itself has many of the hallmarks of successful anti-infective therapies, namely rapid action and broad-spectrum antimicrobial activities. This gives these peptides the potential to become an entirely new thera...     »
Journal title abbreviation:
Int J Mol Sci
Year:
2009
Journal volume:
10
Journal issue:
9
Pages contribution:
3951-70
Language:
eng
Fulltext / DOI:
doi:10.3390/ijms10093951
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19865528
Print-ISSN:
1422-0067
TUM Institution:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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