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Titel:

A refined characterisation of the NeoHepatocyte phenotype necessitates a reappraisal of the transdifferentiation hypothesis.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Riquelme, P; Wundt, J; Hutchinson, JA; Brulport, M; Jun, Y; Sotnikova, A; Girreser, U; Braun, F; Gövert, F; Soria, B; Nüssler, A; Clement, B; Hengstler, JG; Fändrich, F
Abstract:
Under certain culture conditions human peripheral blood monocytes may be induced to express phenotypic markers of non-haematopoietic lineages, including hepatocyte-defining traits. One such example, the NeoHepatocyte, was previously shown to express a broad panel of hepatocyte-like marker antigens and metabolic activities, both in vitro and following engraftment in the liver of immunodeficient mice. In this report, a refined description of NeoHepatocytes, with regard to their expression of xenob...     »
Zeitschriftentitel:
Differentiation
Jahr:
2009
Band / Volume:
77
Heft / Issue:
3
Seitenangaben Beitrag:
263-76
Volltext / DOI:
doi:10.1016/j.diff.2008.10.008
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19272525
Print-ISSN:
0301-4681
TUM Einrichtung:
Klinik und Poliklinik für Unfallchirurgie
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