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Titel:

Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Autor(en):
Schweizerhof, M; Stösser, S; Kurejova, M; Njoo, C; Gangadharan, V; Agarwal, N; Schmelz, M; Bali, KK; Michalski, CW; Brugger, S; Dickenson, A; Simone, DA; Kuner, R
Abstract:
Pain is one of the most severe and debilitating symptoms associated with several forms of cancer. Various types of carcinomas and sarcomas metastasize to skeletal bones and cause spontaneous bone pain and hyperalgesia, which is accompanied by bone degradation and remodeling of peripheral nerves. Despite recent advances, the molecular mechanisms underlying the development and maintenance of cancer-evoked pain are not well understood. Several types of non-hematopoietic tumors secrete hematopoietic...     »
Zeitschriftentitel:
Nat Med
Jahr:
2009
Band / Volume:
15
Heft / Issue:
7
Seitenangaben Beitrag:
802-7
Sprache:
eng
Volltext / DOI:
doi:10.1038/nm.1976
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19525966
Print-ISSN:
1078-8956
TUM Einrichtung:
Chirurgische Klinik und Poliklinik
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