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Title:

Genetics of the Restless Legs Syndrome

Document type:
Review
Author(s):
Winkelmann, J
Abstract:
In genome-wide association studies genetic risk variations for the restless legs syndrome (RLS) have been identified in the genes MEIS1, BTBD9, PTPRD and LBXCOR1/MAP2K5 genes. Carriers of one risk allele have an increased risk to suffer from RLS. Further genetic and/or non-genetic or environmental factors must additionally be present for a person to be afflicted by RLS. It is, however, not known which specific factors are involved in this process. The identified genes are involved in the develop...     »
Journal title abbreviation:
Aktuelle Neurologie
Year:
2009
Journal volume:
36
Journal issue:
10
Pages contribution:
524-527
Language:
de
Print-ISSN:
0302-4350
TUM Institution:
Neurologische Klinik und Poliklinik
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