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Titel:

Long-term B-lymphocyte depletion with rituximab in patients with relapsing-remitting multiple sclerosis.

Dokumenttyp:
Journal Article
Autor(en):
Stüve, O; Leussink, VI; Fröhlich, R; Hemmer, B; Hartung, HP; Menge, T; Kieseier, BC
Abstract:
OBJECTIVE: To describe 2 patients with relapsing-remitting multiple sclerosis (RRMS) receiving long-term treatment with the monoclonal antibody rituximab. The clinical and paraclinical efficacy of rituximab was demonstrated recently in a phase 2 clinical trial in patients with RRMS. DESIGN: Case series. SETTING: Tertiary care university medical center. PATIENTS: Two young patients with highly active RRMS in whom standard therapy had failed before receiving rituximab for up to 48 months. MAIN OUT...     »
Zeitschriftentitel:
Arch Neurol
Jahr:
2009
Band / Volume:
66
Heft / Issue:
2
Seitenangaben Beitrag:
259-61
Sprache:
eng
Volltext / DOI:
doi:10.1001/archneurol.2008.551
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19204165
Print-ISSN:
0003-9942
TUM Einrichtung:
Neurologische Klinik und Poliklinik
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