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Title:

Multiple biological predictors for vulnerable carotid lesions.

Document type:
Journal Article; Article
Author(s):
Pelisek, J; Rudelius, M; Zepper, P; Poppert, H; Reeps, C; Schuster, T; Eckstein, HH
Abstract:
BACKGROUND: In this study a multiscore analysis of various biomarkers including matrix metalloproteinases (MMPs), inflammatory factors and other clinical parameters was performed to establish a set of reliable biomarkers for improved detection of plaque instability in patients with advanced carotid stenosis. METHODS: Study patients (n = 101) were classified as histologically stable (n = 37) or unstable (n = 64). Serum levels of MMP-1, -2, -3, -7, -8, -9, MMP inhibitors TIMP-1, -2, and inflammato...     »
Journal title abbreviation:
Cerebrovasc Dis
Year:
2009
Journal volume:
28
Journal issue:
6
Pages contribution:
601-10
Language:
eng
Fulltext / DOI:
doi:10.1159/000247605
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19844101
Print-ISSN:
1015-9770
TUM Institution:
Fachgebiet Gefäßchirurgie (Prof. Eckstein); Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Statistik und Epidemiologie; Neurologische Klinik und Poliklinik
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