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Title:

Clinical severity of Alzheimer's disease is associated with PIB uptake in PET.

Document type:
Journal Article; Article
Author(s):
Grimmer, T; Henriksen, G; Wester, HJ; Förstl, H; Klunk, WE; Mathis, CA; Kurz, A; Drzezga, A
Abstract:
BACKGROUND: The positron emission tomography (PET) tracer [11C]-Pittsburgh Compound-B ([11C]PIB) allows the in vivo assessment of amyloid plaque burden in the brain. In a cross-sectional study we examined the association between the severity of dementia assessed using the Clinical Dementia Rating scale sum of boxes (CDR-SOB) and [11C]PIB-PET in patients with Alzheimer's disease (AD). METHODS: Patients with probable AD who had an AD-typical [18F]FDG-PET scan were included. Linear regression analy...     »
Journal title abbreviation:
Neurobiol Aging
Year:
2009
Journal volume:
30
Journal issue:
12
Pages contribution:
1902-9
Language:
eng
Fulltext / DOI:
doi:10.1016/j.neurobiolaging.2008.01.016
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18346821
Print-ISSN:
0197-4580
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für Psychiatrie und Psychotherapie
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