Benutzer: Gast  Login
Titel:

Modulation of tissue factor and tissue factor pathway inhibitor-1 by neutrophil proteases.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Steppich, BA; Seitz, I; Busch, G; Stein, A; Ott, I
Abstract:
During systemic inflammation, neutrophil activation is accompanied by endothelial cell damage and hypercoagulability. Activated neutrophils release serine proteases that participate in tissue injury. We sought to investigate the effects of neutrophil proteases on proinflammatory and procoagulant changes in endothelial cells. The effects of elastase (HNE), cathepsin G (CG), and proteinase 3 (PR3) on expression of tissue factor (TF) and tissue factor pathway inhibitor-1 (TFPI) were examined in hum...     »
Zeitschriftentitel:
Thromb Haemost
Jahr:
2008
Band / Volume:
100
Heft / Issue:
6
Seitenangaben Beitrag:
1068-75
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19132232
Print-ISSN:
0340-6245
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie)
 BibTeX