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Title:

Regulation of proliferation of skeletal muscle precursor cells by NADPH oxidase.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Author(s):
Mofarrahi, M; Brandes, RP; Gorlach, A; Hanze, J; Terada, LS; Quinn, MT; Mayaki, D; Petrof, B; Hussain, SN
Abstract:
Skeletal muscle precursor cells are adult stem cells located among muscle fibers. Proliferation, migration, and subsequent differentiation of these cells are critical steps in the repair of muscle injury. We document in this study the roles and mechanisms through which the NAPDH oxidase complex regulates muscle precursor cell proliferation. The NADPH oxidase subunits Nox2, Nox4, p22(phox), p47(phox), and p67(phox) were detected in primary human and murine skeletal muscle precursor cells. In huma...     »
Journal title abbreviation:
Antioxid Redox Signal
Year:
2008
Journal volume:
10
Journal issue:
3
Pages contribution:
559-74
Language:
eng
Fulltext / DOI:
doi:10.1089/ars.2007.1792
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18092937
Print-ISSN:
1523-0864
TUM Institution:
Klinik für Kinderkardiologie und angeborene Herzfehler (Prof. Hess)
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