Login
- Title:
Radiochemical F-18-fluoroarylation of unsaturated alpha-, beta- and gamma-amino acids, application to a radiolabelled analogue of baclofen
- Document type:
- Article
- Author(s):
- Höfling, SB; Hultsch, C; Wester, HJ; Heinrich, MR
- Abstract:
- Unsaturated alpha-, beta- and gamma-amino acids have been investigated as substrates for the reductive Meerwein arylation. Radical reactions of this type have been shown to be a valuable tool for the fast and efficient introduction of the 4-[F-18]fluorophenyl group into precursor molecules allowing short-time syntheses of potential PET radiotracers, which would be more difficult to access by other methods. (C) 2008 Elsevier Ltd. All rights reserved.
- Journal title abbreviation:
- Tetrahedron
- Year:
- 2008
- Journal volume:
- 64
- Journal issue:
- 52
- Pages contribution:
- 11846-11851
- Language:
- eng
- Print-ISSN:
- 0040-4020
- TUM Institution:
- Klinik und Poliklinik für Nuklearmedizin
BibTeX