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Titel:

Radiochemical F-18-fluoroarylation of unsaturated alpha-, beta- and gamma-amino acids, application to a radiolabelled analogue of baclofen

Dokumenttyp:
Article
Autor(en):
Höfling, SB; Hultsch, C; Wester, HJ; Heinrich, MR
Abstract:
Unsaturated alpha-, beta- and gamma-amino acids have been investigated as substrates for the reductive Meerwein arylation. Radical reactions of this type have been shown to be a valuable tool for the fast and efficient introduction of the 4-[F-18]fluorophenyl group into precursor molecules allowing short-time syntheses of potential PET radiotracers, which would be more difficult to access by other methods. (C) 2008 Elsevier Ltd. All rights reserved.
Zeitschriftentitel:
Tetrahedron
Jahr:
2008
Band / Volume:
64
Heft / Issue:
52
Seitenangaben Beitrag:
11846-11851
Sprache:
eng
Print-ISSN:
0040-4020
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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