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Titel:

Influence of Hsp70 and HLA-E on the killing of leukemic blasts by cytokine/Hsp70 peptide-activated human natural killer (NK) cells.

Dokumenttyp:
Journal Article; Article
Autor(en):
Stangl, S; Gross, C; Pockley, AG; Asea, AA; Multhoff, G
Abstract:
This study compared the effects of the human 70-kDa stress protein (Hsp70) peptide, TKDNNLLGRFELSG (TKD), proinflammatory cytokines, or a combination of both on the repertoire of receptors expressed by human natural killer (NK) cells and their capacity to kill human CX colon carcinoma cells, K562 erythroleukemic cells, and leukemic blasts from two patients with acute myelogenous leukemia. Low-dose interleukin (IL) 2/IL-15 and TKD increase the expression density of activatory (NKG2D, NKp30, NKp44...     »
Zeitschriftentitel:
Cell Stress Chaperones
Jahr:
2008
Band / Volume:
13
Heft / Issue:
2
Seitenangaben Beitrag:
221-30
Sprache:
eng
Volltext / DOI:
doi:10.1007/s12192-007-0008-y
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18759005
Print-ISSN:
1355-8145
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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