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Titel:

Absence of the mutated Trp2 allele but a common polymorphism of the COL9A2 collagen gene is associated with early recurrence after lumbar discectomy in a German population.

Dokumenttyp:
Journal Article
Autor(en):
Knoeringer, M; Reinke, A; Trappe, AE; Schlegel, J
Abstract:
Genetic factors seem to play a role in symptomatic lumbar disc disease (LDD). It has been shown previously that a tryptophan mutation of the COL9A2 gene is a major risk factor for LDD in a Finish population. The impact of collagen gene variations on the relapse rate after lumbar discectomy, however, has not been studied so far. Here, we conducted a cross-sectional genotyping study of patients who underwent lumbar discectomy to determine the influence of a COL9A2 mutation on the recurrence rates....     »
Zeitschriftentitel:
Eur Spine J
Jahr:
2008
Band / Volume:
17
Heft / Issue:
3
Seitenangaben Beitrag:
463-7
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00586-007-0548-y
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18080148
Print-ISSN:
0940-6719
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Neurochirurgische Klinik und Poliklinik
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